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Structure paper

TitleMolecular Architecture of DesI: A Key Enzyme in the Biosynthesis of Desosamine
Journal, issue, pagesBiochemistry, Vol. 46, Page 8999-9006, Year 2007
Publish dateApr 25, 2007 (structure data deposition date)
AuthorsBurgie, E.S. / Holden, H.M.
External linksBiochemistry / PubMed:17630700
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-2po3:
Crystal Structure Analysis of DesI in the presence of its TDP-sugar product
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-T4K:
(2R,3R,4S,5S,6R)-3,4-DIHYDROXY-5-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)IMINO]-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL [(2R,3S,5R)-3-HYDROXY-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE

ChemComp-HOH:
WATER

Source
  • streptomyces venezuelae (bacteria)
KeywordsTRANSFERASE / external aldimine / PLP / aminotransferase / TDP-sugar

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