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TitleMolecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria.
Journal, issue, pagesJ. Biol. Chem., Vol. 282, Page 20705-20714, Year 2007
Publish dateMar 20, 2006 (structure data deposition date)
AuthorsGuerin, M.E. / Kordulakova, J. / Schaeffer, F. / Svetlikova, Z. / Buschiazzo, A. / Giganti, D. / Gicquel, B. / Mikusova, K. / Jackson, M. / Alzari, P.M.
External linksJ. Biol. Chem. / PubMed:17510062
MethodsX-ray diffraction
Resolution2.4 - 2.6 Å
Structure data

PDB-2gej:
Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-2gek:
Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-GDD:
GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE

ChemComp-HOH:
WATER

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

Source
  • mycobacterium smegmatis (bacteria)
KeywordsTRANSFERASE / GT4 GLYCOSYLTRANSFERASE / MANNOSYLTRANSFERASE / ROSSMANN FOLD / BINARY COMPLEX

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