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Structure paper

TitleInterdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 104, Page 5800-5805, Year 2007
Publish dateFeb 2, 2007 (structure data deposition date)
AuthorsTakahashi, M. / Kondou, Y. / Toyoshima, C.
External linksProc. Natl. Acad. Sci. Usa / PubMed:17389383
MethodsX-ray diffraction
Resolution2.8 - 3.25 Å
Structure data

PDB-2ear:
P21 crystal of the SR CA2+-ATPase with bound TG
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-2eat:
Crystal structure of the SR CA2+-ATPASE with bound CPA and TG
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-2eau:
Crystal structure of the SR CA2+-ATPASE with bound CPA in the presence of curcumin
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-4ycl:
Crystal structure of the SR CA2+-ATPASE with bound CPA
Method: X-RAY DIFFRACTION / Resolution: 3.25 Å

Chemicals

ChemComp-TG1:
OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), / inhibitor*YM

ChemComp-CZA:
(6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE

ChemComp-PTY:
PHOSPHATIDYLETHANOLAMINE / phospholipid*YM

ChemComp-K:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • oryctolagus cuniculus (rabbit)
KeywordsHYDROLASE / MEMBRANE PROTEIN / P-TYPE ATPASE / HAD FOLD / Ca2+ / ion pump

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