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-Structure paper
Title | Application of fragment screening by X-ray crystallography to beta-Secretase. |
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Journal, issue, pages | J. Med. Chem., Vol. 50, Page 1116-1123, Year 2007 |
Publish date | Jan 2, 2007 (structure data deposition date) |
![]() | Murray, C.W. / Callaghan, O. / Chessari, G. / Cleasby, A. / Congreve, M. / Frederickson, M. / Hartshorn, M.J. / McMenamin, R. / Patel, S. / Wallis, N. |
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Methods | X-ray diffraction |
Resolution | 2.15 - 2.7 Å |
Structure data | ![]() PDB-2of0: ![]() PDB-2ohk: ![]() PDB-2ohl: ![]() PDB-2ohm: ![]() PDB-2ohn: |
Chemicals | ![]() ChemComp-IOD: ![]() ChemComp-DMS: ![]() ChemComp-CMZ: ![]() ChemComp-HOH: ![]() ChemComp-1SQ: ![]() ChemComp-2AQ: ![]() ChemComp-8AP: ![]() ChemComp-4FP: |
Source |
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![]() | HYDROLASE / ALTERNATIVE SPLICING / ALZHEIMER'S DISEASE / ASPARTIC PROTEASE / ASPARTYL PROTEASE / BASE / BETA-SECRETASE / GLYCOPROTEIN / MEMAPSIN 2 / TRANSMEMBRANE / ZYMOGEN |