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Structure paper

TitleCrystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Journal, issue, pagesBiochemistry, Vol. 46, Page 2917-2929, Year 2007
Publish dateNov 30, 2006 (structure data deposition date)
AuthorsTsybovsky, Y. / Donato, H. / Krupenko, N.I. / Davies, C. / Krupenko, S.A.
External linksBiochemistry / PubMed:17302434
MethodsX-ray diffraction
Resolution1.7 - 2.2 Å
Structure data

PDB-2o2p:
Crystal structure of the C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-2o2q:
Crystal structure of the C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADP
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2o2r:
Crystal structure of the C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADPH
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

Source
  • rattus norvegicus (Norway rat)
KeywordsOXIDOREDUCTASE / ALDEHYDE DEHYDROGENASE / FDH

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