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Structure paper

TitleApramycin recognition by the human ribosomal decoding site.
Journal, issue, pagesBlood Cells Mol. Dis., Vol. 38, Page 193-198, Year 2007
Publish dateDec 28, 2006 (structure data deposition date)
AuthorsHermann, T. / Tereshko, V. / Skripkin, E. / Patel, D.J.
External linksBlood Cells Mol. Dis. / PubMed:17258916
MethodsX-ray diffraction
Resolution1.51 - 2.4 Å
Structure data

PDB-2oe5:
1.5 A X-ray crystal structure of Apramycin complex with RNA fragment GGCGUCGCUAGUACCG/GGUACUAAAAGUCGCCC containing the human ribosomal decoding A site: RNA construct with 3'-overhang
Method: X-RAY DIFFRACTION / Resolution: 1.51 Å

PDB-2oe6:
2.4A X-ray crystal structure of unliganded RNA fragment GGGCGUCGCUAGUACC/CGGUACUAAAAGUCGCC containing the human ribosomal decoding A site: RNA construct with 5'-overhang
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-2oe8:
1.8 A X-ray crystal structure of Apramycin complex with RNA fragment GGGCGUCGCUAGUACC/CGGUACUAAAAGUCGCC containing the human ribosomal decoding A site: RNA construct with 5'-overhang
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-MG:
Unknown entry

ChemComp-AM2:
APRAMYCIN / antibiotic*YM

ChemComp-HOH:
WATER

KeywordsRNA / Aminoglycoside antibiotics / Apramycin / Ribosomal decoding site / A site / Homo sapiens / RNA duplex

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