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TitleOctameric structure of the human bifunctional enzyme PAICS in purine biosynthesis.
Journal, issue, pagesJ. Mol. Biol., Vol. 366, Page 1603-1614, Year 2007
Publish dateMay 21, 2006 (structure data deposition date)
AuthorsLi, S.X. / Tong, Y.P. / Xie, X.C. / Wang, Q.H. / Zhou, H.N. / Han, Y. / Zhang, Z.Y. / Gao, W. / Li, S.G. / Zhang, X.C. / Bi, R.C.
External linksJ. Mol. Biol. / PubMed:17224163
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-2h31:
Crystal structure of human PAICS, a bifunctional carboxylase and synthetase in purine biosynthesis
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-CO2:
CARBON DIOXIDE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / LYASE / alpha-beta-alpha

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