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Structure paper

TitleSnapshots of the reaction mechanism of matrix metalloproteinases.
Journal, issue, pagesANGEW. CHEM. INT. ED. ENGL., Vol. 45, Page 7952-7955, Year 2006
Publish dateFeb 21, 2007 (structure data deposition date)
AuthorsBertini, I. / Calderone, V. / Fragai, M. / Luchinat, C. / Maletta, M. / Yeo, K.J.
External linksANGEW. CHEM. INT. ED. ENGL. / PubMed:17096442
MethodsX-ray diffraction
Resolution1.15 - 1.9 Å
Structure data

PDB-2oxu:
Uninhibited form of human MMP-12
Method: X-RAY DIFFRACTION / Resolution: 1.24 Å

PDB-2oxw:
Human MMP-12 complexed with the peptide IAG
Method: X-RAY DIFFRACTION / Resolution: 1.15 Å

PDB-2oxz:
Human MMP-12 in complex with two peptides PQG and IAG
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2oy2:
Human MMP-8 in complex with peptide IAG
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-2oy4:
Uninhibited human MMP-8
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / MMP-12 / Matrix Metalloproteinase / MMP-8

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