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Structure paper

TitleElucidation of Human Choline Kinase Crystal Structures in Complex with the Products Adp or Phosphocholine.
Journal, issue, pagesJ. Mol. Biol., Vol. 364, Page 136-, Year 2006
Publish dateApr 20, 2006 (structure data deposition date)
AuthorsMalito, E. / Sekulic, N. / Too, W.C. / Konrad, M. / Lavie, A.
External linksJ. Mol. Biol. / PubMed:17007874
MethodsX-ray diffraction
Resolution2.15 - 3.1 Å
Structure data

PDB-2cko:
Crystal structure of Human Choline Kinase alpha 2
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-2ckp:
Crystal structure of Human Choline Kinase alpha-2 in complex with ADP
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-2ckq:
Crystal structure of Human Choline Kinase alpha 2 in complex with Phosphocholine
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-DTT:
2,3-DIHYDROXY-1,4-DITHIOBUTANE

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-PC:
PHOSPHOCHOLINE

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / KINASE / CHOLINE KINASE / PHOSPHATYDILCHOLINE / ALTERNATIVE SPLICING / PHOSPHATIDYLCHOLINE / PHOSPHOLIPID SYNTHESIS

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