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-Structure paper
Title | HIV-1 protease mutations and inhibitor modifications monitored on a series of complexes. Structural basis for the effect of the A71V mutation on the active site |
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Journal, issue, pages | J. Med. Chem., Vol. 49, Page 5777-5784, Year 2006 |
Publish date | Apr 28, 2005 (structure data deposition date) |
Authors | Skalova, T. / Dohnalek, J. / Duskova, J. / Petrokova, H. / Hradilek, M. / Soucek, M. / Konvalinka, J. / Hasek, J. |
External links | J. Med. Chem. / PubMed:16970402 |
Methods | X-ray diffraction |
Resolution | 1.93 - 2.3 Å |
Structure data | PDB-1zj7: PDB-1zlf: |
Chemicals | ChemComp-0ZT: ChemComp-HOH: ChemComp-0ZR: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / HIV / PROTEASE / PEPTIDOMIMETIC INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR COMPLEX |