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TitleActivation of the Proapoptotic Death Receptor DR5 by Oligomeric Peptide and Antibody Agonists.
Journal, issue, pagesJ. Mol. Biol., Vol. 361, Page 522-536, Year 2006
Publish dateJun 9, 2006 (structure data deposition date)
AuthorsLi, B. / Russell, S.J. / Compaan, D.M. / Totpal, K. / Marsters, S.A. / Ashkenazi, A. / Cochran, A.G. / Hymowitz, S.G. / Sidhu, S.S.
External linksJ. Mol. Biol. / PubMed:16859704
MethodsX-ray diffraction
Resolution2.32 Å
Structure data

PDB-2h9g:
Crystal structure of phage derived Fab BdF1 with human Death Receptor 5 (DR5)
Method: X-RAY DIFFRACTION / Resolution: 2.32 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM/APOPTOSIS / PHAGE DISPLAY / PROTEIN ENGINEERING / COMBINATORIAL MUTAGENESIS / ANTIBODY LIBRARY / DEATH RECEPTOR-5 / agonists / IMMUNE SYSTEM-APOPTOSIS COMPLEX

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