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TitleStructure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 103, Page 10877-10882, Year 2006
Publish dateAug 17, 2005 (structure data deposition date)
AuthorsWilliams, A.H. / Immormino, R.M. / Gewirth, D.T. / Raetz, C.R.
External linksProc. Natl. Acad. Sci. Usa / PubMed:16835299
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-2aq9:
Structure of E. coli LpxA with a bound peptide that is competitive with acyl-ACP
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / LpxA / peptide inhibitor / acyl ACP / ACP / UDP-glcNac / Lipid A / TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX

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