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TitleHigh-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D(2)-symmetric active site.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 62, Page 695-706, Year 2006
Publish dateApr 22, 2006 (structure data deposition date)
AuthorsNarayana, N.
External linksActa Crystallogr. ,Sect. D / PubMed:16790925
MethodsX-ray diffraction
Resolution1.1 Å
Structure data

PDB-2gqv:
High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site
Method: X-RAY DIFFRACTION / Resolution: 1.1 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsOXIDOREDUCTASE / anisotropic refinement / atomic-resolution structure / folate metabolism / plasmid-encoded R67 DHFR / TMP-resistant DHFR

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