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-Structure paper
Title | Mechanism of substrate recognition by drug-resistant human immunodeficiency virus type 1 protease variants revealed by a novel structural intermediate. |
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Journal, issue, pages | J. Virol., Vol. 80, Page 3607-3616, Year 2006 |
Publish date | Jan 11, 2006 (structure data deposition date) |
![]() | Prabu-Jeyabalan, M. / Nalivaika, E.A. / Romano, K. / Schiffer, C.A. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.44 - 1.85 Å |
Structure data | ![]() PDB-2fns: ![]() PDB-2fnt: |
Chemicals | ![]() ChemComp-ACT: ![]() ChemComp-PO4: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / structural intermediate / substrate recognition / hiv-1 protease / NC-p1 substrate / drug resistance / flap conformation |