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-Structure paper
Title | A Thiamin-bound, Pre-decarboxylation Reaction Intermediate Analogue in the Pyruvate Dehydrogenase E1 Subunit Induces Large Scale Disorder-to-Order Transformations in the Enzyme and Reveals Novel Structural Features in the Covalently Bound Adduct. |
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Journal, issue, pages | J. Biol. Chem., Vol. 281, Page 15296-15303, Year 2006 |
Publish date | Feb 15, 2006 (structure data deposition date) |
![]() | Arjunan, P. / Sax, M. / Brunskill, A. / Chandrasekhar, K. / Nemeria, N. / Zhang, S. / Jordan, F. / Furey, W. |
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Methods | X-ray diffraction |
Resolution | 1.85 - 2.1 Å |
Structure data | ![]() PDB-2g25: ![]() PDB-2g28: |
Chemicals | ![]() ChemComp-MG: ![]() ChemComp-PO4: ![]() ChemComp-TDK: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / PLTHDP / PHOSPHONOLACTYLTHIAMIN DIPHOSPHATE / PYRUVATE DEHYDROGENASE E1 COMPONENT |