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-Structure paper
Title | Two crystal structures of dihydrofolate reductase-thymidylate synthase from Cryptosporidium hominis reveal protein-ligand interactions including a structural basis for observed antifolate resistance. |
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Journal, issue, pages | Acta Crystallogr. ,Sect. F, Vol. 61, Page 258-262, Year 2005 |
Publish date | Feb 17, 2004 (structure data deposition date) |
![]() | Anderson, A.C. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.87 Å |
Structure data | ![]() PDB-1sej: |
Chemicals | ![]() ChemComp-UMP: ![]() ChemComp-F89: ![]() ChemComp-NDP: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / OXIDOREDUCTASE / bifunctional enzyme |