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TitleStructure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 103, Page 3072-3077, Year 2006
Publish dateJul 6, 2005 (structure data deposition date)
AuthorsLin, T.W. / Melgar, M.M. / Kurth, D. / Swamidass, S.J. / Purdon, J. / Tseng, T. / Gago, G. / Baldi, P. / Gramajo, H. / Tsai, S.C.
External linksProc. Natl. Acad. Sci. Usa / PubMed:16492739
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-2a7s:
Crystal Structure of the Acyl-CoA Carboxylase, AccD5, from Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsLIGASE / carboxylase / carboxyltransferase / acetyl-CoA carboxylase / propionyl-CoA carboxylase / Acyl-CoA Carboxylase / mycolic acid / fatty acid / polyketide

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