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-Structure paper
Title | Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680. |
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Journal, issue, pages | Cancer Res., Vol. 66, Page 1007-1014, Year 2006 |
Publish date | Nov 23, 2005 (structure data deposition date) |
![]() | Young, M.A. / Shah, N.P. / Chao, L.H. / Seeliger, M. / Milanov, Z.V. / Biggs, W.H. / Treiber, D.K. / Patel, H.K. / Zarrinkar, P.P. / Lockhart, D.J. ...Young, M.A. / Shah, N.P. / Chao, L.H. / Seeliger, M. / Milanov, Z.V. / Biggs, W.H. / Treiber, D.K. / Patel, H.K. / Zarrinkar, P.P. / Lockhart, D.J. / Sawyers, C.L. / Kuriyan, J. |
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Methods | X-ray diffraction |
Resolution | 1.91 Å |
Structure data | ![]() PDB-2f4j: |
Chemicals | ![]() ChemComp-VX6: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / kinase / kinase inhibitor / abl |