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Structure paper

TitleSmall-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Journal, issue, pagesNat. Chem. Biol., Vol. 1, Page 167-173, Year 2005
Publish dateJun 30, 2005 (structure data deposition date)
AuthorsPhan, A.T. / Kuryavyi, V. / Gaw, H.Y. / Patel, D.J.
External linksNat. Chem. Biol. / PubMed:16408022
MethodsNMR (solution)
Structure data

PDB-2a5p:
Monomeric parallel-stranded DNA tetraplex with snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, NMR, 8 struct.
Method: SOLUTION NMR

PDB-2a5r:
Complex of tetra-(4-n-methylpyridyl) porphin with monomeric parallel-stranded DNA tetraplex, snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, C-MYC promoter, NMR, 6 struct.
Method: SOLUTION NMR

Chemicals

ChemComp-POH:
(1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin

Source
  • homo sapiens (human)
KeywordsDNA / MONOMERIC PARALLEL-STRANDED QUADRUPLEX; C-MYC PROMOTER 3+1 G-TETRAD; SINGLE NUCLEOTIDE CHAIN REVERSAL LOOP; GAG TRIAD; GAAG LOOP

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