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TitleCrystal Structures of Eosinophil-Derived Neurotoxin (Edn) in Complex with the Inhibitors 5'- ATP, Ap(3)A, Ap(4)A, and Ap(5)A.
Journal, issue, pagesBiochemistry, Vol. 45, Page 416-, Year 2006
Publish dateAug 24, 2005 (structure data deposition date)
AuthorsBaker, M.D. / Holloway, D.E. / Swaminathan, G.J. / Acharya, K.R.
External linksBiochemistry / PubMed:16401072
MethodsX-ray diffraction
Resolution0.98 - 2 Å
Structure data

PDB-2bzz:
Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A
Method: X-RAY DIFFRACTION / Resolution: 0.98 Å

PDB-2c01:
Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A
Method: X-RAY DIFFRACTION / Resolution: 1.24 Å

PDB-2c02:
Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2c05:
Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A
Method: X-RAY DIFFRACTION / Resolution: 1.86 Å

Chemicals

ChemComp-AP5:
BIS(ADENOSINE)-5'-PENTAPHOSPHATE

ChemComp-ACY:
ACETIC ACID

ChemComp-HOH:
WATER

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-B4P:
BIS(ADENOSINE)-5'-TETRAPHOSPHATE

Source
  • homo sapiens (human)
KeywordsHYDROLASE / ENDONUCLEASE / EOSINOPHIL / NUCLEASE / RIBONUCLEASE / RNASE US / RNASE-2 / INHIBITOR / 5'-ATP / AP3A / AP4A / AP5A / CHEMOTAXIS / GLYCOPROTEIN / POLYMORPHISM / SENSORY TRANSDUCTION

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