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TitleNovel class III phosphoribosyl diphosphate synthase: structure and properties of the tetrameric, phosphate-activated, non-allosterically inhibited enzyme from Methanocaldococcus jannaschii
Journal, issue, pagesJ. Mol. Biol., Vol. 354, Page 815-828, Year 2005
Publish dateAug 11, 2004 (structure data deposition date)
AuthorsKadziola, A. / Jepsen, C.H. / Johansson, E. / McGuire, J. / Larsen, S. / Hove-Jensen, B.
External linksJ. Mol. Biol. / PubMed:16288921
MethodsX-ray diffraction
Resolution2.65 - 2.8 Å
Structure data

PDB-1u9y:
Crystal Structure of Phosphoribosyl Diphosphate Synthase from Methanocaldococcus jannaschii
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-1u9z:
Crystal Structure of Phosphoribosyl Diphosphate Synthase Complexed with AMP and Ribose 5-Phosphate
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-R5P:
RIBOSE-5-PHOSPHATE

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

Source
  • methanocaldococcus jannaschii (archaea)
KeywordsTRANSFERASE / PRPP synthase / PRPP synthase; ribose 5-phosphate; adenosine 5'-monophosphate

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