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TitleKinetic, Inhibition and Structural Studies on 3-Oxoacyl-Acp Reductase from Plasmodium Falciparum, a Key Enzyme in Fatty Acid Biosynthesis.
Journal, issue, pagesBiochem. J., Vol. 393, Page 447-, Year 2006
Publish dateAug 26, 2005 (structure data deposition date)
AuthorsWickramasinghe, S.R. / Inglis, K.A. / Urch, J.E. / Muller, S. / Van Aalten, D.M.F. / Fairlamb, A.H.
External linksBiochem. J. / PubMed:16225460
MethodsX-ray diffraction
Resolution1.5 Å
Structure data

PDB-2c07:
Oxoacyl-ACP reductase of Plasmodium falciparum
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
KeywordsOXIDOREDUCTASE / FABG / SHORT-CHAIN ALCOHOL REDUCTASE / FATTY ACID BIOSYNTHESIS / APICOPLAST / KETOACYL-ACP REDUCTASE

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