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TitleCrystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 102, Page 15018-15023, Year 2005
Publish dateApr 14, 2005 (structure data deposition date)
AuthorsBiterova, E.I. / Turanov, A.A. / Gladyshev, V.N. / Barycki, J.J.
External linksProc. Natl. Acad. Sci. Usa / PubMed:16217027
MethodsX-ray diffraction
Resolution2.6 - 3 Å
Structure data

PDB-1zdl:
Crystal Structure of Mouse Thioredoxin Reductase Type 2
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-1zkq:
Crystal structure of mouse thioredoxin reductase type 2
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsOXIDOREDUCTASE / Selenocysteine / thioredoxin / reductase / flavoprotein

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