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Structure paper

TitleMechanisms of Product Feedback Regulation and Drug Resistance in Cytidine Triphosphate Synthetases from the Structure of a CTP-Inhibited Complex(,).
Journal, issue, pagesBiochemistry, Vol. 44, Page 13491-13499, Year 2005
Publish dateJul 19, 2005 (structure data deposition date)
AuthorsEndrizzi, J.A. / Kim, H. / Anderson, P.M. / Baldwin, E.P.
External linksBiochemistry / PubMed:16216072
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-2ad5:
Mechanisms of feedback regulation and drug resistance of CTP synthetases: structure of the E. coli CTPS/CTP complex at 2.8-Angstrom resolution.
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-CTP:
CYTIDINE-5'-TRIPHOSPHATE

ChemComp-HOH:
WATER

Source
  • escherichia coli k12 (bacteria)
KeywordsLIGASE / Rossmann fold / P-loop ATPase / interfacial active site

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