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TitleOligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety
Journal, issue, pagesJ. Mol. Biol., Vol. 353, Page 53-67, Year 2005
Publish dateJul 21, 2005 (structure data deposition date)
AuthorsRamasamy, V. / Ramakrishnan, B. / Boeggeman, E. / Ratner, D.M. / Seeberger, P.H. / Qasba, P.K.
External linksJ. Mol. Biol. / PubMed:16157350
MethodsX-ray diffraction
Resolution1.9 - 2 Å
Structure data

PDB-2ae7:
Crystal Structure of Human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4GAL-T1) in Complex with Pentasaccharide
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2aec:
Crystal Structure of Human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4GAL-T1) in Complex with GlcNAc-beta1,2-Man-alpha1,6-Man-beta-OR
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2aes:
Crystal Structure of Human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4Gal-T1) in Complex with GlcNAc-beta1,2-Man-alpha1,3-Man-beta-OR
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2agd:
Crystal Structure of Human M340H-Beta-1,4-Galactosyltransferase-I(M340H-B4Gal-T1) in Complex with GlcNAc-beta1,4-Man-alpha1,3-Man-beta-OR
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-2ah9:
Crystal Structure of Human M340H-Beta-1,4-Galactosyltransferase-I (M340H-B4Gal-T1) in Complex with Chitotriose
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-UDH:
6-AMINOHEXYL-URIDINE-C1,5'-DIPHOSPHATE

ChemComp-GOL:
GLYCEROL

ChemComp-DIO:
1,4-DIETHYLENE DIOXIDE

ChemComp-HOH:
WATER

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / beta1 / 4-Galactosyltransferase-I; Pentasaccharide; Closed conformation; Mutant / 4-Galactosyltransferase-I; Trisaccharide; Closed conformation; Mutant / 4-Galactosyltransferase-I; Trisaccharide; 13arm; Closed conformation; Mutant / 4-Galactosyltransferase-I; Trisaccharide; Chitotriose; Closed conformation; Mutant

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