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-Structure paper
| Title | Discovery of substituted maleimides as liver x receptor agonists and determination of a ligand-bound crystal structure. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 48, Page 5419-5422, Year 2005 |
| Publish date | Jul 19, 2005 (structure data deposition date) |
 Authors | Jaye, M.C. / Krawiec, J.A. / Campobasso, N. / Smallwood, A. / Qiu, C. / Lu, Q. / Kerrigan, J.J. / De Los Frailes Alvaro, M. / Laffitte, B. / Liu, W.S. ...Jaye, M.C. / Krawiec, J.A. / Campobasso, N. / Smallwood, A. / Qiu, C. / Lu, Q. / Kerrigan, J.J. / De Los Frailes Alvaro, M. / Laffitte, B. / Liu, W.S. / Marino, J.P. / Meyer, C.R. / Nichols, J.A. / Parks, D.J. / Perez, P. / Sarov-Blat, L. / Seepersaud, S.D. / Steplewski, K.M. / Thompson, S.K. / Wang, P. / Watson, M.A. / Webb, C.L. / Haigh, D. / Caravella, J.A. / Macphee, C.H. / Willson, T.M. / Collins, J.L. |
 External links | J. Med. Chem. / PubMed:16107141 |
| Methods | X-ray diffraction |
| Resolution | 2.8 Å |
| Structure data |  PDB-2acl: |
| Chemicals |  ChemComp-REA:  ChemComp-L05:  ChemComp-HOH: |
| Source |
|
 Keywords | TRANSCRIPTION / nuclear hormone receptor ligand binding domain transcription factor three layered a-helix fold |
homo sapiens (human)
mus musculus (house mouse)