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Structure paper

TitleStructural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme
Journal, issue, pagesNature, Vol. 437, Page 838-844, Year 2005
Publish dateJun 13, 2005 (structure data deposition date)
AuthorsHiggins, L.J. / Yan, F. / Liu, P. / Liu, H.W. / Drennan, C.L.
External linksNature / PubMed:16015285
MethodsX-ray diffraction
Resolution1.8 - 2.4 Å
Structure data

PDB-1zz6:
Crystal Structure of Apo-HppE
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1zz7:
Crystal Structure of FeII HppE in Complex with Substrate form 1
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-1zz8:
Crystal Structure of FeII HppE in Complex with Substrate Form 2
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1zz9:
Crystal Structure of FeII HppE
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1zzb:
Crystal Structure of CoII HppE in Complex with Substrate
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1zzc:
Crystal Structure of CoII HppE in Complex with Tris Buffer
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-FE2:
Unknown entry

ChemComp-S0H:
(S)-2-HYDROXYPROPYLPHOSPHONIC ACID

ChemComp-SO4:
SULFATE ION

ChemComp-CO:
Unknown entry

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

Source
  • streptomyces wedmorensis (bacteria)
KeywordsOXIDOREDUCTASE / Mononuclear Iron Enzyme / Apoprotein / Cupin / Substrate-Enzyme Complex / holo-HppE

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