タイトル | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum |
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ジャーナル・号・ページ | J. Biol. Chem., Vol. 280, Page 33387-33396, Year 2005 |
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掲載日 | 2004年10月13日 (構造データの登録日) |
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著者 | Goettig, P. / Brandstetter, H. / Groll, M. / Goehring, W. / Konarev, P.V. / Svergun, D.I. / Huber, R. / Kim, J.-S. |
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リンク | J. Biol. Chem. / PubMed:15994304 |
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手法 | X線回折 |
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解像度 | 1.8 - 3.2 Å |
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構造データ | PDB-1xqv: Crystal structure of inactive F1-mutant G37A 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-1xqw: Crystal structure of F1-mutant S105A complex with PHE-LEU 手法: X-RAY DIFFRACTION / 解像度: 2.0 Å PDB-1xqx: Crystal structure of F1-mutant S105A complex with PCK 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-1xqy: Crystal structure of F1-mutant S105A complex with PRO-LEU-GLY-GLY 手法: X-RAY DIFFRACTION / 解像度: 3.2 Å PDB-1xrl: Crystal structure of active site F1-mutant Y205F complex with inhibitor PCK 手法: X-RAY DIFFRACTION / 解像度: 1.82 Å PDB-1xrm: Crystal structure of active site F1-mutant E213Q soaked with peptide Ala-Phe 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-1xrn: Crystal structure of active site F1-mutant E213Q soaked with peptide Phe-Ala 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-1xro: Crystal structure of active site F1-mutant E213Q soaked with peptide Phe-Leu 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-1xrp: Crystal structure of active site F1-mutant E213Q soaked with peptide Pro-Leu-Gly-Gly 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-1xrq: Crystal structure of active site F1-mutant E245Q soaked with peptide Phe-Leu 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-1xrr: Crystal structure of active site F1-mutant E245Q soaked with peptide Pro-Pro 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å |
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化合物 | ChemComp-PHK: (2R,3S)-3-AMINO-1-CHLORO-4-PHENYL-BUTAN-2-OL
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由来 | - thermoplasma acidophilum (好酸性)
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キーワード | HYDROLASE / ALPHA-BETA HYDROLASE / CAGED ACTIVE SITE / SUBSTRATE BINDING / OXYANION POCKET / CATALYTIC TRIAD / NUCLEOPHILE / CHLOROMRTHYL KETONE INHIBITOR / PEPTIDE CLEAVAGE / SUBSTRATE RECOGNITION / HYDROGEN BONDED NETWORK / CHLOROMETHYL KETONE INHIBITOR / DIPROLINE |
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