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TitleCrystal Structures of the HIV-1 Inhibitory Cyanobacterial Protein MVL Free and Bound to Man3GlcNAc2: STRUCTURAL BASIS FOR SPECIFICITY AND HIGH-AFFINITY BINDING TO THE CORE PENTASACCHARIDE FROM N-LINKED OLIGOMANNOSIDE.
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 29269-29276, Year 2005
Publish dateApr 26, 2005 (structure data deposition date)
AuthorsWilliams, D.C. / Lee, J.Y. / Cai, M. / Bewley, C.A. / Clore, G.M.
External linksJ. Biol. Chem. / PubMed:15937331
MethodsX-ray diffraction
Resolution1.8 - 1.9 Å
Structure data

PDB-1zhq:
Crystal structure of apo MVL
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-1zhs:
Crystal structure of MVL bound to Man3GlcNAc2
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • microcystis viridis (bacteria)
KeywordsSUGAR BINDING PROTEIN / HIV-1 / MVL / cyanobacteria / carbohydrate binding

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