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Structure paper

TitleKinetic stabilization of an oligomeric protein by a single ligand binding event
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 127, Page 5540-5551, Year 2005
Publish dateJul 16, 2004 (structure data deposition date)
AuthorsWiseman, R.L. / Johnson, S.M. / Kelker, M.S. / Foss, T. / Wilson, I.A. / Kelly, J.W.
External linksJ. Am. Chem. Soc. / PubMed:15826192
MethodsX-ray diffraction
Resolution1.69 Å
Structure data

PDB-1u21:
transthyretin with tethered inhibitor on one monomer.
Method: X-RAY DIFFRACTION / Resolution: 1.69 Å

Chemicals

ChemComp-P2C:
2-[(3,5-DICHLORO-4-TRIOXIDANYLPHENYL)AMINO]BENZOIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHORMONE/GROWTH FACTOR / transthyretin / amyloid / HORMONE-GROWTH FACTOR COMPLEX

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