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Structure paper

TitleThe Mutation G145S in Prfa, a Key Virulence Regulator of Listeria Monocytogenes, Increases DNA-Binding Affinity by Stabilizing the Hth Motif
Journal, issue, pagesMol. Microbiol., Vol. 56, Page 433-, Year 2005
Publish dateNov 26, 2004 (structure data deposition date)
AuthorsEiting, M. / Hagelueken, G. / Schubert, W.-D. / Heinz, D.W.
External linksMol. Microbiol. / PubMed:15813735
MethodsX-ray diffraction
Resolution2.3 - 2.7 Å
Structure data

PDB-2beo:
PrfA, Transcriptional Regulator In Listeria Monocytogenes
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-2bgc:
PrfA-G145S, a constitutive active mutant of the Transcriptional Regulator In L.monocytogenes
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-GLN:
GLUTAMINE

ChemComp-CL:
Unknown entry

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-ACM:
ACETAMIDE

ChemComp-HOH:
WATER

ChemComp-DTU:
(2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL

ChemComp-DTT:
2,3-DIHYDROXY-1,4-DITHIOBUTANE

Source
  • listeria monocytogenes (bacteria)
KeywordsTRANSCRIPTION / BACTERIAL INFECTION / HUMAN PATHOGEN / TRANSCRIPTIONAL REGULATOR / ACTIVATOR / VIRULENCE

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