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TitleOfloxacin-Like Antibiotics Inhibit Pneumococcal Cell Wall-Degrading Virulence Factors
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 19948-, Year 2005
Publish dateMar 15, 2005 (structure data deposition date)
AuthorsFernandez-Tornero, C. / Garcia, E. / Lopez, R. / Pascual-Teresa, B.D. / Gimenez-Gallego, G. / Romero, A.
External linksJ. Biol. Chem. / PubMed:15769740
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-2bml:
Ofloxacin-like antibiotics inhibit pneumococcal cell wall degrading virulence factors
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-P6G:
HEXAETHYLENE GLYCOL / precipitant*YM

ChemComp-XED:
DEXTROFLOXACINE

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • streptococcus pneumoniae (bacteria)
KeywordsCHOLINE-BINDING DOMAIN / CELL WALL ATTACHMENT / OFLOXACIN-LIKE ANTIBIOTICS

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