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Structure paper

TitleStrong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 14114-14121, Year 2005
Publish dateNov 17, 2003 (structure data deposition date)
AuthorsDe Genst, E. / Silence, K. / Ghahroudi, M.A. / Decanniere, K. / Loris, R. / Kinne, J. / Wyns, L. / Muyldermans, S.
External linksJ. Biol. Chem. / PubMed:15659390
MethodsX-ray diffraction
Resolution1.4 - 1.85 Å
Structure data

PDB-1ri8:
Crystal Structure of the Camelid Single Domain Antibody 1D2L19 in complex with Hen Egg White Lysozyme
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-1rjc:
Crystal structure of the camelid single domain antibody cAb-Lys2 in complex with hen egg white lysozyme
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

Source
  • camelus dromedarius (Arabian camel)
  • gallus gallus (chicken)
KeywordsIMMUNE SYSTEM/HYDROLASE / beta sandwich / immunoglobulin fold / VHH-lysozyme complex / alpha-beta orthogonal bundle / IMMUNE SYSTEM-HYDROLASE COMPLEX / protein-protein hetero complex

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