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-Structure paper
Title | Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition. |
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Journal, issue, pages | Nat. Struct. Mol. Biol., Vol. 11, Page 1192-1197, Year 2004 |
Publish date | Feb 4, 2004 (structure data deposition date) |
![]() | Ohren, J.F. / Chen, H. / Pavlovsky, A. / Whitehead, C. / Zhang, E. / Kuffa, P. / Yan, C. / McConnell, P. / Spessard, C. / Banotai, C. ...Ohren, J.F. / Chen, H. / Pavlovsky, A. / Whitehead, C. / Zhang, E. / Kuffa, P. / Yan, C. / McConnell, P. / Spessard, C. / Banotai, C. / Mueller, W.T. / Delaney, A. / Omer, C. / Sebolt-Leopold, J. / Dudley, D.T. / Leung, I.K. / Flamme, C. / Warmus, J. / Kaufman, M. / Barrett, S. / Tecle, H. / Hasemann, C.A. |
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Methods | X-ray diffraction |
Resolution | 2.4 - 3.2 Å |
Structure data | ![]() PDB-1s9i: ![]() PDB-1s9j: |
Chemicals | ![]() ChemComp-MG: ![]() ChemComp-ATP: ![]() ChemComp-5EA: ![]() ChemComp-BBM: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / PROTEIN KINASE-LIGAND-MgATP COMPLEX / PROTEIN-PROTEIN INTERACTIONS |