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TitleCHARACTERIZATION OF THE INTERACTION BETWEEN RAR/RXR HETERODIMERS AND TRANSCRIPTIONAL COACTIVATORS THROUGH STRUCTURAL AND FLUORESCENCE ANISOTROPY STUDIES
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 1625-1633, Year 2005
Publish dateSep 7, 2004 (structure data deposition date)
AuthorsPogenberg, V. / Guichou, J.F. / Vivat-Hannah, V. / Kammerer, S. / Perez, E. / Germain, P. / De Lera, A.R. / Gronemeyer, H. / Royer, C.A. / Bourguet, W.
External linksJ. Biol. Chem. / PubMed:15528208
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-1xdk:
Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-9CR:
(9cis)-retinoic acid / anticancer, antineoplastic*YM

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsHORMONE/GROWTH FACTOR RECEPTOR / Nuclear Receptor / Coactivator / Ligand / HORMONE-GROWTH FACTOR RECEPTOR COMPLEX

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