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Structure paper

TitleThe Synaptic Acetylcholinesterase Tetramer Assembles Around a Polyproline-II Helix
Journal, issue, pagesEmbo J., Vol. 23, Page 4394-, Year 2004
Publish dateMay 20, 2004 (structure data deposition date)
AuthorsDvir, H. / Harel, M. / Bon, S. / Liu, W.-Q. / Vidal, M. / Garbay, C. / Sussman, J.L. / Massoulie, J. / Silman, I.
External linksEmbo J. / PubMed:15526038
MethodsX-ray diffraction
Resolution2.35 Å
Structure data

PDB-1vzj:
Structure of the tetramerization domain of acetylcholinesterase: four-fold interaction of a WWW motif with a left-handed polyproline helix
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / ACETYLCHOLINESTERASE / SYNAPSE / NEUROTRANSMITTER DEGRADATION / ALTERNATIVE SPLICING / DISEASE MUTATION.

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