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-Structure paper
Title | Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant |
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Journal, issue, pages | Biochemistry, Vol. 43, Page 14111-14117, Year 2004 |
Publish date | May 21, 2004 (structure data deposition date) |
Authors | Sun, T. / Bethel, C.R. / Bonomo, R.A. / Knox, J.R. |
External links | Biochemistry / PubMed:15518561 |
Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | PDB-1tdg: PDB-1tdl: |
Chemicals | ChemComp-MA4: ChemComp-TBE: ChemComp-MDD: ChemComp-MRD: ChemComp-MPD: ChemComp-HOH: ChemComp-EPE: |
Source |
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Keywords | HYDROLASE / S130G SHV-1 class A beta-lactamase / penicillinase / beta-lactam hydrolase / detergent binding / inhibitor complex / tazobactam / aldehyde / cymal-6 / class A beta-lactamase / drug design |