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| Title | Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant |
|---|---|
| Journal, issue, pages | Biochemistry, Vol. 43, Page 14111-14117, Year 2004 |
| Publish date | May 21, 2004 (structure data deposition date) |
Authors | Sun, T. / Bethel, C.R. / Bonomo, R.A. / Knox, J.R. |
External links | Biochemistry / PubMed:15518561 |
| Methods | X-ray diffraction |
| Resolution | 1.8 Å |
| Structure data | ![]() PDB-1tdg: ![]() PDB-1tdl: |
| Chemicals | ![]() ChemComp-MA4: ![]() ChemComp-TBE: ![]() ChemComp-MDD: ![]() ChemComp-MRD: ![]() ChemComp-MPD: ![]() ChemComp-HOH: ![]() ChemComp-EPE: |
| Source |
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Keywords | HYDROLASE / S130G SHV-1 class A beta-lactamase / penicillinase / beta-lactam hydrolase / detergent binding / inhibitor complex / tazobactam / aldehyde / cymal-6 / class A beta-lactamase / drug design |
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klebsiella pneumoniae (bacteria)
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