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TitleAllergy vaccine engineering: epitope modulation of recombinant Bet v 1 reduces IgE binding but retains protein folding pattern for induction of protective blocking-antibody responses.
Journal, issue, pagesJ Immunol., Vol. 173, Page 5258-5267, Year 2004
Publish dateOct 6, 1999 (structure data deposition date)
AuthorsHolm, J. / Gajhede, M. / Ferreras, M. / Henriksen, A. / Ipsen, H. / Larsen, J.N. / Lund, L. / Jacobi, H. / Millner, A. / Wurtzen, P.A. / Spangfort, M.D.
External linksJ Immunol. / PubMed:15470071
MethodsX-ray diffraction
Resolution2.15 Å
Structure data

PDB-1qmr:
BIRCH POLLEN ALLERGEN BET V 1 MUTANT N28T, K32Q, E45S, P108G
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • betula verrucosa (European white birch)
KeywordsALLERGEN / PATHOGENESIS-RELATED PROTEIN

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