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Structure paper

TitleStructural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 101, Page 8563-8568, Year 2004
Publish dateApr 5, 2004 (structure data deposition date)
AuthorsZhao, K. / Harshaw, R. / Chai, X. / Marmorstein, R.
External linksProc. Natl. Acad. Sci. Usa / PubMed:15150415
MethodsX-ray diffraction
Resolution1.5 - 1.75 Å
Structure data

PDB-1szc:
Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-1szd:
Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-CNA:
CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-APR:
ADENOSINE-5-DIPHOSPHORIBOSE

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsGENE REGULATION / Sir2 / Sirtuin / histone deacetylase / hst2 / protein deacetylase

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