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TitleA bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones
Journal, issue, pagesChem. Biol., Vol. 11, Page 565-573, Year 2004
Publish dateJan 14, 2004 (structure data deposition date)
AuthorsVetting, M.W. / Magnet, S. / Nieves, E. / Roderick, S.L. / Blachard, J.S.
External linksChem. Biol. / PubMed:15123251
MethodsX-ray diffraction
Resolution2 - 3 Å
Structure data

PDB-1s3z:
Aminoglycoside N-Acetyltransferase AAC(6')-Iy in Complex with CoA and Ribostamycin
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1s5k:
Aminoglycoside N-Acetyltransferase AAC(6')-Iy in Complex with CoA and N-terminal His(6)-tag (crystal form 1)
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1s60:
Aminoglycoside N-Acetyltransferase AAC(6')-Iy in Complex with CoA and N-terminal His(6)-tag (crystal form 2)
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-SO4:
SULFATE ION

ChemComp-COA:
COENZYME A

ChemComp-RIO:
RIBOSTAMYCIN / antibiotic*YM

ChemComp-HOH:
WATER

Source
  • salmonella enteritidis (bacteria)
KeywordsTRANSFERASE / GNAT / N-acetyltransferase / acetyltransferase / aminoglycoside / CoA / ribostamycin

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