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TitleThe crystal structure of a (-) gamma-lactamase from an Aureobacterium species reveals a tetrahedral intermediate in the active site.
Journal, issue, pagesJ. Mol. Biol., Vol. 338, Page 519-532, Year 2004
Publish dateMar 10, 2003 (structure data deposition date)
AuthorsLine, K. / Isupov, M.N. / Littlechild, J.A.
External linksJ. Mol. Biol. / PubMed:15081810
MethodsX-ray diffraction
Resolution1.73 Å
Structure data

PDB-1hkh:
unligated gamma lactamase from an Aureobacterium species
Method: X-RAY DIFFRACTION / Resolution: 1.73 Å

PDB-1hl7:
Gamma lactamase from an Aureobacterium species in complex with 3a,4,7,7a-tetrahydro-benzo [1,3] dioxol-2-one
Method: X-RAY DIFFRACTION / Resolution: 1.73 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-BD1:
3A,4,7,7A-TETRAHYDRO-BENZO [1,3] DIOXOL-2-ONE

Source
  • microbacterium (bacteria)
  • microbacterium sp. (bacteria)
KeywordsHYDROLASE / ALPHA/BETA HYDROLASE / CO-FACTOR FREE HALOPEROXIDASE / TETRAHEDRAL INTERMEDIATE

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