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Structure paper

TitleCrystal structure and mechanism of a bacterial fluorinating enzyme
Journal, issue, pagesNature, Vol. 427, Page 561-565, Year 2004
Publish dateDec 6, 2003 (structure data deposition date)
AuthorsDong, C. / Huang, F. / Deng, H. / Schaffrath, C. / Spencer, J.B. / O'Hagan, D. / Naismith, J.H.
External linksNature / PubMed:14765200
MethodsX-ray diffraction
Resolution1.8 - 2.67 Å
Structure data

PDB-1rqp:
Crystal structure and mechanism of a bacterial fluorinating enzyme
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-1rqr:
Crystal structure and mechanism of a bacterial fluorinating enzyme, product complex
Method: X-RAY DIFFRACTION / Resolution: 2.67 Å

Chemicals

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-HOH:
WATER

ChemComp-5FD:
5'-FLUORO-5'-DEOXYADENOSINE

ChemComp-MET:
METHIONINE

Source
  • streptomyces cattleya (bacteria)
KeywordsTRANSFERASE / fluorinase / central 7 stranded beta sheets / anti-parallel beta sheets

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