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TitleStructural Insights into the Human and Avian IMP Cyclohydrolase Mechanism via Crystal Structures with the Bound XMP Inhibitor.
Journal, issue, pagesBiochemistry, Vol. 43, Page 1171-1183, Year 2004
Publish dateJun 6, 2003 (structure data deposition date)
AuthorsWolan, D.W. / Cheong, C.G. / Greasley, S.E. / Wilson, I.A.
External linksBiochemistry / PubMed:14756553
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1pkx:
Crystal Structure of human ATIC in complex with XMP
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-XMP:
XANTHOSINE-5'-MONOPHOSPHATE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / HYDROLASE / ATIC / AICAR transformylase / IMP Cyclohydrolase / xanthosine monophosphate / purine biosynthesis

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