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Structure paper

TitleStructure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.
Journal, issue, pagesEmbo J., Vol. 23, Page 282-293, Year 2004
Publish dateJul 29, 2003 (structure data deposition date)
AuthorsLewis, H.A. / Buchanan, S.G. / Burley, S.K. / Conners, K. / Dickey, M. / Dorwart, M. / Fowler, R. / Gao, X. / Guggino, W.B. / Hendrickson, W.A. ...Lewis, H.A. / Buchanan, S.G. / Burley, S.K. / Conners, K. / Dickey, M. / Dorwart, M. / Fowler, R. / Gao, X. / Guggino, W.B. / Hendrickson, W.A. / Hunt, J.F. / Kearins, M.C. / Lorimer, D. / Maloney, P.C. / Post, K.W. / Rajashankar, K.R. / Rutter, M.E. / Sauder, J.M. / Shriver, S. / Thibodeau, P.H. / Thomas, P.J. / Zhang, M. / Zhao, X. / Emtage, S.
External linksEmbo J. / PubMed:14685259
MethodsX-ray diffraction
Resolution2.2 - 3 Å
Structure data

PDB-1q3h:
mouse CFTR NBD1 with AMP.PNP
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1r0w:
Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) apo
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1r0x:
Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) with ATP
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1r0y:
Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) with ADP
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-1r0z:
Phosphorylated Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) with ATP
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-1r10:
Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) with ATP, I4122 space group
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-ACY:
ACETIC ACID

ChemComp-HOH:
WATER

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • mus musculus (house mouse)
KeywordsMEMBRANE PROTEIN / ABC transporter nucleotide binding domain / TRANSPORT PROTEIN

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