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Structure paper

TitleStructure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 9497-9503, Year 2004
Publish dateJun 17, 2003 (structure data deposition date)
AuthorsSchoch, G.A. / Yano, J.K. / Wester, M.R. / Griffin, K.J. / Stout, C.D. / Johnson, E.F.
External linksJ. Biol. Chem. / PubMed:14676196
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-1pq2:
Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-PLM:
PALMITIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / CYTOCHROME P450 / CYP2C8 / MEMBRANE PROTEIN / TAXOL 6-HYDROXYLASE

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