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Structure paper

TitleThe crystal structure of AMP-bound PDE4 suggests a mechanism for phosphodiesterase catalysis
Journal, issue, pagesBiochemistry, Vol. 42, Page 13220-13226, Year 2003
Publish dateJun 23, 2003 (structure data deposition date)
AuthorsHuai, Q. / Colicelli, J. / Ke, H.
External linksBiochemistry / PubMed:14609333
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1ptw:
The Crystal Structure of AMP-Bound PDE4 Suggests a Mechanism for Phosphodiesterase Catalysis
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / catalytic mechanism / cAMP hydrolysis crystal structure / binuclear catalysis

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