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Structure paper

TitleA metal-ligand-mediated intersubunit allosteric switch in related SmtB/ArsR zinc sensor proteins.
Journal, issue, pagesJ. Mol. Biol., Vol. 333, Page 683-695, Year 2003
Publish dateSep 25, 2003 (structure data deposition date)
AuthorsEicken, C. / Pennella, M.A. / Chen, X. / Koshlap, K.M. / VanZile, M.L. / Sacchettini, J.C. / Giedroc, D.P.
External linksJ. Mol. Biol. / PubMed:14568530
MethodsX-ray diffraction
Resolution1.7 - 2.3 Å
Structure data

PDB-1r1t:
Crystal structure of the cyanobacterial metallothionein repressor SmtB in the apo-form
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-1r1u:
Crystal structure of the metal-sensing transcriptional repressor CzrA from Staphylococcus aureus in the apo-form
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1r1v:
Crystal structure of the metal-sensing transcriptional repressor CzrA from Staphylococcus aureus in the Zn2-form
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1r22:
Crystal structure of the cyanobacterial metallothionein repressor SmtB (C14S/C61S/C121S mutant) in the Zn2alpha5-form
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1r23:
Crystal structure of the cyanobacterial metallothionein repressor SmtB in the Zn1-form (one Zn(II) per dimer)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-ZN:
Unknown entry

Source
  • synechococcus elongatus pcc 7942 (bacteria)
  • staphylococcus aureus (bacteria)
KeywordsTRANSCRIPTION REPRESSOR / Zinc / transcriptional regulation / winged HTH protein / DNA binding / DNA binding protein / DNA binding Transcriptional regulation

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