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TitleCrystal structure of the heterodimeric complex of LXRalpha and RXRbeta ligand-binding domains in a fully agonistic conformation
Journal, issue, pagesEmbo J., Vol. 22, Page 4625-4633, Year 2003
Publish dateJul 3, 2003 (structure data deposition date)
AuthorsSvensson, S. / Ostberg, T. / Jacobsson, M. / Norstrom, C. / Stefansson, K. / Hallen, D. / Johansson, I.C. / Zachrisson, K. / Ogg, D. / Jendeberg, L.
External linksEmbo J. / PubMed:12970175
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-1uhl:
Crystal structure of the LXRalfa-RXRbeta LBD heterodimer
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-MEI:
(2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID

ChemComp-444:
N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / ligand-binding domain

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