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Structure paper

TitleA helical twist-induced conformational switch activates cleavage in the hammerhead ribozyme.
Journal, issue, pagesJ. Mol. Biol., Vol. 332, Page 327-336, Year 2003
Publish dateFeb 12, 2003 (structure data deposition date)
AuthorsDunham, C.M. / Murray, J.B. / Scott, W.G.
External linksJ. Mol. Biol. / PubMed:12948485
MethodsX-ray diffraction
Resolution2.85 - 3 Å
Structure data

PDB-1nyi:
Crosslinked Hammerhead Ribozyme Initial State
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-1q29:
Hammerhead Ribozyme with 5'-5' G-G linkage: Conformational change experiment
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-CO:
Unknown entry

ChemComp-5GP:
GUANOSINE-5'-MONOPHOSPHATE

Source
  • synthetic construct (others)
KeywordsRNA / Hammerhead Ribozyme crosslink conformational change / Hammerhead Ribozyme

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